[12][13][14] The chemotherapy agent vincristine is extracted from a closely related species, Catharanthus roseus,[15][16][17] and is used to treat some leukemias,[18] lymphomas,[19] and childhood cancers,[20] as well as several other types of cancer and some non-cancerous conditions. Latin Name: Vinca minor Common name: Periwinkle Family: Apocynaceae Parts used: Aerial (leaf) Constituents: Indole alkaloids (Vincristine & Vinblastine), tannins, volatile oils (terpenoids), flavonoids, saponins, phytosterols. Latin name : Catharanthus roseus, formerly Vinca rosea or Lochnera rosea. Pliny the Elder (23-79 CE), a Roman naturalist and philosopher, wrote that in his time it was widely cultivated as an ornamental plant. For obstructions of mucus in the intestines and lungs, diarrhoea, congestions, haemorrhages, etc., Periwinkle Tea is a good remedy. This means it can make constipation worse. Mesophyll is differentiated into palisade and spongy parenchyma. A second alkaloid, vincristine, is utilized for treating leukemia in children. Uses, Benefits, Cures, Side Effects, Nutrients in Vinca Major. Methanesulfonate is a good leaving group because of the efficient delocalization of negative charge between three oxygen atoms. Copyright 10. The fruit consists of a pair of divergent follicles; the dry fruit dehisces along one rupture site to release seeds.[7][8]. MULTIPLE CHOICE QUESTIONS : 1. This plant is cultivated as an ornamental plant and found in tropical regions like Africa, Australia, Eastern Europe, South Florida, India, Taiwan and Thailand. Medicinal Use. It has been credited with significantly improving the survival rate of victims of childhood leukemia. It also contains 'reserpine', which reduces high blood pressure. Vinca alkaloids are the earliest microtubule-targeting agents approved for clinical use. Medicinal use: Has a long tradition in herbal medicine, particularly in the treatment of diabetes. Despite serious safety concerns, periwinkle is used for “ brain health ” (increasing blood circulation in the brain, supporting brain metabolism, increasing mental productivity, preventing memory and concentration problems and feebleness, improving memory and thinking ability, … Charles W. Kane | Applied Medical Botany. Liquid extract of root and rhizome, DER 1:1, extraction solvent ethanol 40% Saratikov (1974) reports that in 1969, the Ministry of Health of the former USSR recommended to allow the medical utilis ation and industrial production of the liquid extract of the . Side effects: Therefore, the rest of the information in this section should be used for information only, and not for practical use. Tamil: Nityakalyani. Over 70 different alkaloids, including vincristine and vinblastine, have been extracted from vinca rosea with astonishing results. It contains the alkaloid "vincamine", which is used by the pharmaceutical industry as a cerebral stimulant and vasodilator. Herbal preparations in medicinal use reported from the M ember States: A. In that last roll, it is used to treat wounds and to reduce menstrual flow. Medicinal actions: Atringent, cerebral circulatory stimulant, cytotoxic (anti-cancer). Hindi: Sadabahar. Names of Vinca Major in various languages of the world are also given. 5-9 layered, loosely arranged with intercellular spaces. Though the leaves of the plant is used the most for medicinal uses, the flowers also are used for treating eye infections by making an eyewash out of them. Decoctions of the plant have been used to treat ocular inflammation, diabetes, hemorrhages, insect stings, and cancers.2, 4, 5, 6, 7 Lesser Periwinkle or common periwinkle (vinca minor) is most often the species within the periwinkle family that is used for natural medicinal purposes. Vinca is used to help treat hemorrhages, skin problems, blood circulation problems, and diabetes. Prohibited Content 3. It contains the alkaloid "vincamine", which is used by the pharmaceutical industry as a cerebral stimulant and vasodilator. The plant has been widely used in It is used internally in the treatment of excessive menstruation, abnormal uterine bleeding, vaginal discharge and hardening of … Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. In that last roll, it is used to treat wounds and to reduce menstrual flow. It is stated that Vinca roseus/ Catharathus roseus is toxic or highly poisonous. Constipation: Periwinkle has a drying effect on tissues. Sadabahar plants contain various alkaloids that are useful in conditions such as cancer, diabetes, high blood pressure and stroke. List of Medicinal Plants, their uses. [] VBL has been used as an integral part of medicinal treatment regimens for testicular carcinoma and both Hodgkin and non … It contains the alkaloid "vincamine", which is used by the pharmaceutical industry as a cerebral stimulant and vasodilator. It is used internally in the treatment of excessive menstruation, abnormal uterine bleeding, vaginal discharge and hardening of … The chemotherapy agent vincristine is extracted from a closely related species, Catharanthus roseus, and is used to treat some leukemias, lymphomas, and childhood cancers, as well as several other types of cancer and some non-cancerous conditions. The vinca alkaloids include at least 86 alkaloids extracted from plants in the genus Vinca. • Medicinal chemistry approaches led to the discovery of new effective derivatives. Vinca alkaloid: A medication in a class of anticancer drugs that inhibit cancer cell growth by stopping cell division (mitosis). Mode of use: This plant is a toxic medicinal plant and its use should only be directed by a doctor . • Also it helps to treat non-Hodgkin’s lymphomas . Disclaimer 9. [3][4][5][6] The English name periwinkle is shared with the related genus Catharanthus (and also with the common seashore mollusc, Littorina littorea). Despite serious safety concerns, periwinkle is used for “ brain health ” (increasing blood circulation in the brain, supporting brain metabolism, increasing mental productivity, preventing memory and concentration problems and feebleness, improving memory and thinking ability, and preventing early aging of brain cells). It also contains "reserpine", which reduces high blood pressure. The parts that grow above the ground are used to make medicine. Abstract. It is an optimal herb for avoiding Blood Cancer. It also contains "reserpine", which reduces high blood pressure. Cancer still represents a “nightmare” worldwide, causing annually millions of victims. In Ayurvedic medicine the leaves, … They do not have cross-resistance with drugs that alkylate deoxyribonucleic acid (DNA) and have a different mechanism of action. (iii) In the treatment of leukemia in children. Vinca (/ˈvɪŋkə/;[2] Latin: vincire "to bind, fetter") is a genus of flowering plants in the family Apocynaceae, native to Europe, northwest Africa and southwest Asia. [22] Dimeric alkaloids such as vincristine and vinblastine are produced by the coupling the smaller indole alkaloids vindoline and catharanthine. Because of its properties of detoxification and counteracting poison, it is used to relieve wasp stings. The bioactive ingredients vinblastine and vincristine are used in the treatment of leukemia and Hodgkin’s lymphoma. History. Vinca plants are subshrubs or herbaceous, and have slender trailing stems 1–2 m (3.3–6.6 ft) long but not growing more than 20–70 cm (8–27.5 in) above ground; the stems frequently take root where they touch the ground, enabling the plant to spread widely. Vincristine and vinblastine are used for the treatment of various types of cancer such as Hodgkin's disease, breast cancer, skin cancer and lymphoblastic leukemia. Primary Menu Skip to content. (iv) Vinca is used in hypertension. Plagiarism Prevention 4. 5. Today it grows throughout much of the world and plantations have been established on most continents in the warmer climates. Decoctions of the … Don't use it. • Also it helps to treat non-Hodgkin’s lymphomas . Since the discovery of vincamine in the leaves, the plant has been used herbally to treat arteriosclerosis and for dementia due to insufficient blood supply to … Today it grows throughout the world, and plantations have been established on continents with warmer climates. Search. How can someone prepare it at home in order to avoid toxicity and which parts of the pkants are used for treating which diseases. Today it grows throughout the world, and plantations have been established on continents with warmer climates. Sadabahar Plant (Nithyakalyani) Side Effects: Though external application does not have any side effects, internal consumption is best done under medical supervision as it is very toxic in certain dosages. A few stomata are seen on the upper epidermis. So below chart gives an idea of the List of Medicinal Plants and uses. The vinca alkaloids are also called antimitotic or antimicrotubule agents, or mitotic inhibitors. Content Filtrations 6. Vinblastine is a chemical analogue of vincristine and is also used to treat various forms of cancer. They are also traditionally used in older cemeteries as an evergreen maintenance-free ground cover. Rhodiola. TOS 7. Medicinal use. The plant was introduced in Europe during the mid-1700s, during which time it was cultivated as an ornamental. It is dried whole plant of Catharanthus roseus. (iii) In the treatment of leukemia in children. (i) Dimeric Indole bases of monoterpene type. Uses: (i) Antineoplastic (antimitotic= Cytostatic = anticancer antitumour). If you want to heal your existing diseases and speed up healing in the natural way, you should take advantage of miracles that nature offers you. There are different shades of periwinkle, but the pink and white variety are used for medicinal purposes. It contains the alkaloid 'vincamine', which is used by the pharmaceutical industry as a cerebral stimulant and vasodilator. In Italy is is called the plant of death. Vinca alkaloids interfere with microtubules (cell structures that help move chromosomes during mitosis). Two of the species, Vinca major and Vinca minor, are extensively cultivated as a flowering evergreen ornamental plant. Voir cette photo intitulée P138504e Rosy Periwinkle Vinca Rosea Valued For Medicinal Uses Such As Cancer. There are at least 86 alkaloids extracted from plants in the Vinca genus. How Vinca Major is effective for various diseases is listed in repertory format. Vinca Properties: The properties of this plant include its anti-cancer, anti-hemorrhagic and anti-diabetic action. How Vinca Major is effective for various diseases is listed in repertory format. Other alkaloids include reserpine, reserpinine, akuammicine, majdine, vinerine, ervine, vineridine, tombozine, vincamajine, vincanine, vincanidine, vincamone, apovincamine, vincaminol, desoxyvincaminol, vincorine and perivincine. … Content Guidelines 2. Latin name: Vinca minor Family: Apocynaceae (Dogbane Family) Medicinal use of Lesser Periwinkle: The plant is sedative and tonic. Cancer still represents a “nightmare” worldwide, causing annually millions of victims. Medication made from this alkaloid is used to treat Hodgkin’s lymphoma, an immune system cancer. Uses: (i) Antineoplastic (antimitotic= Cytostatic = anticancer antitumour). The vinca alkaloids include at least 86 alkaloids extracted from plants in the genus Vinca. It can relieve muscle pain and depression. Strips of collenchyma appear below the upper epidermis and above the lower epidermis. Latin name : Catharanthus roseus, formerly Vinca rosea or Lochnera rosea. (v) Fruit- a follicle, cylindrical and many seeded. Hindi: Sadabahar. Catharanthus roseus may be used for treating asthma. It is known as an astringent agent and as good for controlling excessive blood flow. It has been credited with significantly improving the survival rate of victims of childhood leukemia. The related plant Vinca minor (common periwinkle, myrtle) is used as a ground cover.1, 2, 3, 4. Vascular strands are seen here at times. The alkaloids may also offer sedative and tranquilizing properties. Periwinkle Health Benefits . • Medicinal chemistry approaches led to the discovery of new effective derivatives. What is vinca . (iii) In the treatment of leukemia in children. Methanesulfonate is a good leaving group because of the efficient delocalization of negative charge between three oxygen atoms. Vinca is also useful for the treatment of malaria. In the root, stems, leaves, and seeds of periwinkle flowers found anti-cancer alkaloids content. Vinblastine is a chemical analogue of vincristine[13][16][21] and is also used to treat various forms of cancer. Vinca alkaloids are the earliest microtubule-targeting agents approved for clinical use. What is Vinca for: This plant helps to treat bleeding, skin problems, blood circulation problems and diabetes . Calcium oxalate crystals of any kind are totally absent. Vincristine and vinblastine combined with ch… They were originally derived from the common periwinkle plant, have been synthesized, and include vinblastine, vincristine, vindesine and vinorelbine. (iii) Leaves – Ovate, oblong, glossy above glaucous below; (iv) Flowers – 2 to 3 in cymes, axillary and terminal clusters. In traditional medicine, the leaf juice has been used to treat wasp stings; a gargle is used for sore throats, and flower extracts are used for infants' eyewash. Periwinkle Health Benefits . Taken internally, they are used in the treatment of internal bleeding, heavy menstrual bleeding and nosebleeds[254]. Vinca major is used in herbal practice for its astringent and tonic properties in menorrhagia and in haemorrhages generally. Astringent Bitter Detergent Homeopathy Hypotensive Purgative Sedative Stomachic Tonic Vasodilator The plant is astringent, bitter, detergent, sedative, stomachic and tonic[4, 7, 21, 53, 165, 238]. Common Name: Madagascar periwinkle, Rosy periwinkle, Vinca. The chemotherapy agent vincristine is extracted from a closely related species, Catharanthus roseus, and is used to treat some leukemias, lymphomas, and childhood cancers, as well as several other types of cancer and some non-cancerous conditions. Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. Botanical Name: Catharanthus roseus. Periwinkle was already referred to as medicinal plant at the time of Pedanius Dioscorides (1st century AD), who recommended the use of the herb for a toothache and poisonous insect stings and animal bites. Dimeric alkaloids such as vincristine and vinblastine are produce… Single layered cells elongated and compact. Sadabahar plants contain various alkaloids that are useful in conditions such as cancer, diabetes, high blood pressure and stroke. Chinese medicine uses the extracts of the plant to treat conditions such as diabetes, malaria, leukemia, and Hodgkin's disease. Unfortunately, this plant can also be poisonous if used inappropriately. It is Antiviral in nature, therefore, it potentially work against Viral Infections. They were originally derived from the common periwinkle plant, have been synthesized, and include vinblastine, vincristine, vindesine and vinorelbine. Before publishing your articles on this site, please read the following pages: 1. The bioactive ingredients vinblastine and vincristine are used in the treatment of leukemia and Hodgkin’s lymphoma. MULTIPLE CHOICE QUESTIONS : 1. Plants For A Future can not take any responsibility for any adverse effects from the use of plants. The plant was introduced in Europe during the mid-1700s and was cultivated as an ornamental. The chemotherapy agent known as vincristine is extracted from Vinca rosea (Catharanthus roseus) is used to treat diseases such as diabetes, leukemias, high blood pressure, lymphomas, stroke, and childhood cancers as well as several other types of cancer and some non-cancerous conditions. 5. Uses/Medicinal Uses : • It is used to treat lymphomas • The Hodgkin’s disease is treated by vinca because it contains vinblastin as a chemical constituent. Since the discovery of vincamine in the leaves, the plant has been used herbally to treat arteriosclerosis and for dementia due to insufficient blood supply to the brain[254]. Taken internally, they are used in the treatment of internal bleeding, heavy menstrual bleeding and nosebleeds[254]. The vinca alkaloids have been generally included in combination chemotherapy regimens for medicinal therapies. (ii) In the treatment of Hodgkin’s disease. • Innovative Vinca alkaloids-based therapies are under investigation. Image Guidelines 5. Same as upper epidermis but the number of stomata are more. Madagascar periwinkle is a plant. Vinca rosea (Catharanthus roseus), normally known as Sadabahar; is a decorative plant in addition to having effective medicinal values, belongs to the family Apocynaceae. The high reactivity of the epoxide ring toward nucleophilic groups in biomolecules is the basis of the use of ethylene oxide to sterilize substances that would be damaged by heat, including medical supplies such as bandages, sutures, and surgical implements. Vincristine, extracted from Vinca rosea L. (current name Catharanthus roseus), is a type of chemotherapy called a vinca alkaloid used to treat some leukemias, lymphomas and childhood cancers, as well as several other types of cancer and some non-cancerous conditions. Due to Antidiabetic properties, it regulates blood Sugar levels and prevents Diabetes. For obstructions of mucus in the intestines and lungs, diarrhoea, congestions, haemorrhages, etc., Periwinkle Tea is a good remedy. Sign up here Receive updates by email when more home remedies are added to the site. Catharanthus roseus may be used for treating asthma. Abstract. Catharanthus roseus is diuretic in nature and increases urine. In cases of scurvy and for relaxed sore throat and inflamed tonsils, it may also be used as a gargle. Flowers and leaves have the potential to be a source of medicine for leukemia and Hodgkin’s disease. Areas affected include parts of Australia, New Zealand, Canada, and the United States, especially coastal California. In the Middle Ages, periwinkle was often recommended as a treatment for a sore throat, noseb… Name of plant: Source of plant (Scientific) Uses: 1: Aconite: Aconitum ferox –plant root: Leprosy, cholera,catarrh : 2: Aloe vera: Aloe barbadensis: Succulent leaves. Single layered with more or less rectangular cells, the outer walls of which are circularized. There are different shades of periwinkle, but the pink and white variety are used for medicinal purposes. Medicinal use: chemical constituents Vinca minor contains more than 50 alkaloids, including vincamine. The plant was introduced in Europe during the mid-1700s and was cultivated as an ornamental. The plant has been widely used in tropical folk medicine. Periwinkle (Vinca Major) is also known as small and large periwinkle, though not very often in use and is a plant with a lot of benefits. [10][11], The vinca alkaloids include at least 86 alkaloids extracted from plants in the genus Vinca. They are used to treat cancer.” Vincristine, marketed as Oncovin, is used to treat leukemia in children. Its scientific name is Vinca rosea and can be bought in natural products stores or manipulation pharmacies. Names of Vinca Major in various languages of the world are also given. Vinca alkaloid: A medication in a class of anticancer drugs that inhibit cancer cell growth by stopping cell division (mitosis). They are used to treat cancer.” Vincristine, marketed as Oncovin, is used to treat leukemia in children. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects. Vinorelbine, a newer semi-synthetic chemotherapeutic agent, is used in the treatment of non-small-cell lung cancer[16][24] and is prepared either from the natural products leurosine[25][26] or catharanthine and vindoline,[16][27] in both cases by first preparing anhydrovinblastine. Other alkaloids include reserpine, reserpinine, akuammicine, majdine, vinerine, ervine, vineridine, tombozine, vincamajine, vincanine, vincanidine, vincamone, apovincamine, vincaminol, desoxyvincaminol, vincorine and perivincine. Always seek advice from a professional before using a plant medicinally. Tamil: Nityakalyani. They have been used to treat diabetes, … Yet it said to cure so many diseases. Privacy Policy 8. MEDICINAL USES. Bases on flower colour, three varieties are known namely – alba-white, ocillata-white with pink or carmine red eyes and roseus -with rose coloured flowers. Latin name: Vinca minor Family: Apocynaceae (Dogbane Family) Medicinal use of Lesser Periwinkle: The plant is sedative and tonic. In cases of scurvy and for relaxed sore throat and inflamed tonsils, it may also be used as a gargle. List of various diseases cured by Vinca Major. • Acute lymphocytic leukemia is treated by the help of vincristine part of vinca herb. The plant has been widely used in tropical folk medicine. (ii) In the treatment of Hodgkin’s disease. Here you can learn the benefits of periwinkle, which is used after leaves are collected and dried in the shade. Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. The leaves are bitter, detergent and stomachic[7]. The leaves are opposite, simple broad laneolate to ovate, 1–9 cm (0.5–3.5 in) long and 0.5–6 cm (0.20–2.36 in) broad; they are evergreen in four species, but deciduous in the herbaceous V. herbacea, which dies back to the root system in winter. Catharanthus roseus is also useful for the treatment of Asthma. In the root, stems, leaves, and seeds of periwinkle flowers found anti-cancer alkaloids content. Periwinkle is UNSAFE for anyone to use, but people with certain conditions are especially at risk for harmful side effects. (i) Antineoplastic (antimitotic= Cytostatic = anticancer antitumour). This is followed by cortical parenchyma. The substance named Vincristine, which is used as a chemotherapy drug to treat several types of cancer is also found in this plant. Uses/Medicinal Uses : • It is used to treat lymphomas • The Hodgkin’s disease is treated by vinca because it contains vinblastin as a chemical constituent. The chemotherapy agent known as vincristine is extracted from Vinca rosea (Catharanthus roseus) is used to treat diseases such as diabetes, leukemias, high blood pressure, lymphomas, stroke, and childhood cancers as well as several other types of cancer and some non-cancerous conditions. • Innovative Vinca alkaloids-based therapies are under investigation. The high reactivity of the epoxide ring toward nucleophilic groups in biomolecules is the basis of the use of ethylene oxide to sterilize substances that would be damaged by heat, including medical supplies such as bandages, sutures, and surgical implements. It is known as an astringent agent and as good for controlling excessive blood flow. [9] Many cultivars are available, with different plant, leaf, and flower colors, sizes, and habits. Madagascar periwinkle is used for diabetes, cancer, sore throat, cough, insect bite, and many other conditions, but there is no good scientific evidence to support these uses. Medicinal use: chemical constituents Vinca minor contains more than 50 alkaloids, including vincamine. It has Antibacterial properties which fight against Bacteria. It is used internally in the treatment of excessive menstruation, abnormal uterine bleeding, vaginal discharge and … It also stops bleeding from the wound directly. A well developed vascular bundle is seen in the centre of midrib. [13][23] In addition, the nootropic agent vincamine is derived from Vinca minor. The plant is used against insect bites. Epidermal layers of lamina are continuous in the midrib region also. Sometimes very short trichomes are also seen. Vinca is a medicinal plant, also known as Good Night or Cat's Claw, widely used in the treatment of circulatory problems. The vinca alkaloids are also called antimitotic or antimicrotubule agents, or mitotic inhibitors. (ii) In the treatment of Hodgkin’s disease. Vinca major is used in herbal practice for its astringent and tonic properties in menorrhagia and in haemorrhages generally. Madagascar or "Rosy" Periwinkleis by far the most important plant medicinally, generating hundreds of millions per year in the pharmaceutical industry as a promising addition to the arsenal against childhood leukemia, Hodgkin's Disease, testicular cancer and cancerous tumors, high blood Trouver des images haute résolution de qualité dans la banque d'images Getty Images. Properties of vinca . List of various diseases cured by Vinca Major. It is widely used in the treatment of Lung Cancer. [15][16][27], "World Checklist of Selected Plant Families", "Reductive C—C bond formation after epoxide opening via electron transfer", "Modifications on the basic skeletons of vinblastine and vincristine", "Chemotherapy for Acute Lymphocytic Leukemia", "Chemotherapy for Chronic Myeloid Leukemia", "Chemotherapy for Brain and Spinal Cord Tumors in Children", "Total Synthesis of Vinblastine, Related Natural Products, and Key Analogues and Development of Inspired Methodology Suitable for the Systematic Study of Their Structure-Function Properties", "Chemotherapy for Non-Small Cell Lung Cancer", "Safety and efficacy of vinorelbine in the treatment of non-small cell lung cancer", "Plants Profile for Vinca major (bigleaf periwinkle)", "Neotropical Plant Portal Research Checklist: Peru", "Plants Profile for Vinca minor (common periwinkle)", https://en.wikipedia.org/w/index.php?title=Vinca&oldid=984931139, Taxonbars using multiple manual Wikidata items, Creative Commons Attribution-ShareAlike License, This page was last edited on 22 October 2020, at 23:20. Plant and its use should only be directed by a doctor please read the following pages:.! Vinca Major is effective for various diseases is listed in repertory format States, especially coastal.... Obtained from the common periwinkle plant before using a plant medicinally 70 different alkaloids, including vincristine and is useful... Of diabetes, have been established on most continents in the genus Vinca how Vinca Major and Vinca minor:... Dimeric indole bases of monoterpene type effect on tissues from this alkaloid is to... Survival rate of victims alkaloid: a medication in a class of cancer Vinca for: this plant to. Following pages: 1 are available, with different plant, have been synthesized, and United! Articles on this site, please read the following pages: 1 continuous in the treatment of Hodgkin s. It has been credited with significantly improving the survival rate of victims are at least 86 alkaloids extracted from M! 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Nosebleeds [ 254 ] s lymphomas unfortunately, this plant include its anti-cancer, anti-hemorrhagic anti-diabetic... Minor contains more than 50 alkaloids, including vincristine and vinblastine, vincristine, vindesine vinorelbine. Source of medicine for leukemia and Hodgkin ’ s disease used in herbal for. Alkaloids extracted from plants in the intestines and lungs, diarrhoea,,. Traditionally used in the treatment of internal bleeding, heavy menstrual bleeding nosebleeds... It regulates blood Sugar levels and prevents diabetes = anticancer antitumour ) site, please the. The ground are used in the treatment of malaria section should be used as groundcover in garden landscapes container. Periwinkle: the properties of this plant is sedative and tranquilizing properties with a bulbous base of... To be a source of medicine for leukemia and Hodgkin ’ s lymphoma immune cancer. Were originally derived from Vinca minor, are extensively cultivated as an ornamental alkaloids. 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